Old Age (Older Than 75 Years), Reduced Platelet Counts Or Plateletĭysfunction, Uncontrolled Hypertension, Anemia, Genetic Factors,Įlevated Fall Risk, Stroke, And 2 Points For Re-Bleeding).4 The newīleeding risk score HAS-BLED (Hypertension, Abnormal renal/liverįunction, Stroke history, Bleeding history, Labile International

HEMORR2HAGES score (Hepatic Or Renal Disease, Ethanol Abuse, Malignancy, Mellitus, Stroke, Vascular disease, Age 65 to 74 years, Sex category),3 Score (Congestive heart failure, Hypertension, Age ≥75 years, Diabetes Score (1 point for Congestive heart failure, Hypertension, Age 75 yearsĪnd older, and Diabetes, and 2 points for previous Stroke), CHA2DS2-VASc Treatments has improved the vascular diseases in patients, the risk ofīleeding remains a significant issue.2 The risk of bleeding has beenĮvaluated in many clinical trials using various schemas like CHADS2 Vascular risk patients.1 Though the antithrombotic combination Recent years, antithrombotic therapy is often chosen to treat such high Pulmonary thromboembolism and venous thromboembolism worldwide in the Thrombotic diseases- atrial fibrillation, prosthetic heart valves,Ĭardioembolic ischemic cerebral disease, myocardial infarction, A HAS-BLED risk score of ≥3 is associated with TIMI major bleeding.ĭue to a large increase in the number of patients with Stroke history, bleeding predisposition, labile INR's are the HAS-BLED risk factors which are significant (0.05) with the TIMI Bleeding Criteria.Ĭonclusion: There was a linear correlation between the HAS-BLED risk score and the TIMI bleeding criteria-higher the risk score the more frequent is the incidence of major bleeding. Two antiplatelets + One anticoagulant is the most common combination which caused bleeding in 41. Bleeding occurred mostly in males 79.4% and a HAS-BLED Score of ≥3 has been observed in 67.6% (n=23) patients out of 34 bled patients. Among them 34 (9.1%) bleeding cases were reported with mean (± SD) age of 57.8 (☑4.19) years. Results: A total of 400 cases were collected during the 8-month study period, of which 372 satisfied the inclusion criteria. Pearson Correlation Statistics (Fisher's z Transformation) is applied to assess the association between HAS-BLED risk factors and the total risk score with bleeding criteria. Consecutive patients were enrolled and followed from the date of admission till the adverse events are perceived/date of discharge. Methods: A prospective observational study in a cohort of patients for a period of 8 months, at one of the tertiary care center-Krishna Institute of Medical Sciences, Hyderabad, was conducted. Objectives: To monitor the different antithrombotic drug combinations, determine the incidence, magnitude of bleeding and the association of HAS-BLED risk scoring schema with the magnitude of bleeding as defined using TIMI bleeding criteria.

Timi major bleeding